An extract from grape seeds forces laboratory leukemia cells to commit cell suicide, according to researchers from the University of Kentucky. They found that within 24 hours, 76 percent of leukemia cells had died after being exposed to the extract. The investigators, who report their findings in the January 1, 2009, issue of Clinical Cancer Research, a journal of the American Association for Cancer Research, also teased apart the cell signaling pathway associated with use of grape seed extract that led to cell death, or apoptosis. They found that the extract activates JNK, a protein that regulates the apoptotic pathway.
While grape seed extract has shown activity in a number of laboratory cancer cell lines, including skin, breast, colon, lung, stomach and prostate cancers, no one had tested the extract in hematological cancers nor had the precise mechanism for activity been revealed.
Hematological cancers – leukemia, lymphoma and myeloma – accounted for an estimated 118,310 new cancer cases and almost 54,000 deaths in 2006, ranking these cancers as the fourth leading cause of cancer incidence and death in the U.S.
It’s important to note that this recent study was conducted in a lab, not in human beings, so its conclusions cannot necessarily be directly translated into saying something like “grapeseed extract cures cancer,” for example. However, it does indicate quite convincingly that if the unique phytochemical molecules found in grapeseed extract can be delivered to leukemia cells with sufficient potency, they may play an important role in cancer cells destroying themselves, thereby protecting the whole organism from runaway cancer.
Another important finding in the University of Kentucky study is that the grapeseed extract was not toxic to normal, healthy cells even as it helped cancer cells commit suicide.
This is hugely important because it shows, yet again, that Mother Nature’s medicine is far safer than medicine created by Man. Conventional chemotherapy chemicals are extremely toxic to healthy cells, which is why chemotherapy causes permanent brain damage (“chemo brain”), kidney damage and heart damage. Grapeseed extract, however, causes no such damage, and there has never been a person who died from eating grapes.
The best way to get grapeseed extract is by eating grape seeds. The second best way is to get it mixed in with a superfood powder or supplement that contains no filler. The least preferred way to get it is by taking a GSE capsule made with a lot of filler, so keep that in mind.